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Postdoctoral Scientist at the Institute for Ophthalmic Research

The lab of Prof. Marius Ueffing at the Institute for Ophthalmic Research, University of Tübingen, Germany, is looking for a

Postdoctoral Scientist in Protein Network Analysis for Age-related Macular Degeneration

The Ueffing lab is applying systems medicine approaches to retinal degeneration. The lab runs a state-of-the-art facility for mass spectrometric analysis of proteins and metabolites. Within the EYE-RISK consortium the group collaborates with research institutions, eye clinics and industry to investigate the molecular drivers and risks of Age-related macular degeneration (AMD), Europe’s most frequent cause for blindness. EYE-RISK applies new methods in genetics, biochemistry and bioinformatics to build a robust and validated model of AMD pathways and risks. For insight into our methods and approaches see Boldt et al. 2016, Körtvely et al. 2016, Sacco et al. 2014, Kiel et al. 2011, Kiel et al. 2017.

Your tasks:

  • assembling the map of protein complexes and interactions in AMD
  • validating computational simulations of disease pathways by proteomics and cell biology (cf. Boldt et al. Nat Comm. 2016 for methods)
  • analysing biochemical properties of proteins coded by AMD risk variants (cf. Körtvely et al. Hum Mol Genet. 2016 for methods)
  • validating risk algorithms by analysing patient samples

Your profile:

  • background in proteomics, biochemistry or molecular biology
  • creativity & team spirit
  • experience in vision science, neurobiology, molecular genetics or protein science
  • talents in method development
  • decent publication record

We offer an environment for advanced research and close interaction with scientists in the lab and associated laboratories. You will work - in the systems medicine consortium EYE-RISK including leading European investigators, - in advanced analysis of the largest AMD patient cohorts in Europe, - within one of the leading Centers for Ophthalmology in Europe, - in a large and diverse lab firmly embedded into the neuroscience community on campus, - using the full spectrum of –omics technologies including SRM, phosphoproteomics, lipidomics, metabolomics, transcriptomics, RNAseq, and you can receive a competitive salary (according to your experience and within the legal framework of employment laws).

The position is available from the earliest date possible, initially limited to the duration of the EYE-RISK project until 30.04.2019, with plans for a further extension.

We offer remuneration in accordance with TV-L (collective wage agreement for the Public Service of the German Federal state) in addition to all the customary benefits granted to employees working in Public services. Severely handicapped persons with equal qualifications are given preferential consideration. The University of Tübingen is anxious to increase its quota of female scientific staff, and herefore emphatically requests women to apply for this position. The Administration of the University Hospital is responsible for all employment matters. Personnel appointments will be made pursuant to the fundamental stipulations of the legal statutes for universities in Germany.

Please include your cover letter, CV and the names of three academic references into a single pdf file and send your application to